Whereas, HDL cholesterol had been adversely correlated with hs-CRP amounts. Multivariate regression analysis utilizing design 1 and 2, revealed that in identifying hs-CRP levels, triglyceride and BMI were taking a big part. SUMMARY Hs-CRP correlates with extent of atherosclerosis, and high triglyceride and BMI is closely connected with large hs-CRP levels in patients with dyslipidemia. Copyright © 2019 Dewa Ayu Swastini, Ida Ayu Dewi Wiryanthini, Ni Luh Putu Ariastuti, Agus Muliantara.BACKGROUND Infection is the most typical diseases in developing country, including Indonesia. Bacteria that often causes infection is Escherichia coli and Staphylococcus aureus. Among the old-fashioned plants which you can use as an antibacterial is lidah mertua. AIM The purpose of this study would be to know the profile of chemical substances by slim level chromatography method and determine the antibacterial activity of Lidah Mertua will leave by in vitro. TECHNIQUES This research carried out an experimentally making use of non-polar, semipolar, and polar as solvents to get extract against E. coli and S. aureus as microbial screening. The antibacterial task using agar diffusion approach to get minimal inhibitory focus (MIC). OUTCOMES caused by the research on thin level chromatography showed that the substances within the Lidah Mertua leaves were polifenol, steroids and alkaloids. The information gotten were tabulated and analysed descriptively. The anti-bacterial activity show that n-hexane extract does not offer inhibitory activity. MIC value show that aethyl acetate herb of lidah mertua leaves inhibited the development immune genes and pathways of E. coli and S. aureus at concentration 50 mg/mL and 25 mg/mL with diameters of inhibition zone is 8.50 mm and 8.20 mm and methanol extract of lidah mertua actually leaves inhibited the development of E. coli and S. aureus at concentration 12.5 mg/mL and 25 mg/mL with diameters of inhibition zone is 8.46 mm and 8.32 mm. CONCLUSION The profile of chemical compounds by slim layer chromatography technique indicated that the compounds included in the Lidah Mertua leaves were polifenol, steroids and alkaloids. The anti-bacterial activity show that n-hexane extract does not supply inhibitory task, but aethyl acetate plant of lidah mertua actually leaves inhibited the rise of E. coli and S. aureus. Copyright © 2019 Yessi Febriani, Vriezka Mierza, Novi Putri Handayani, Surismayanti Surismayanti, Ibrenaita Ginting.BACKGROUND CMC is one of the water-soluble polysaccharide derivatives acquired from cellulose. Alkalization and carboxymethylation procedure will affect the caliber of the CMC. The utilization of a mixture of combined solvents and varying alkali levels in the synthesis means of CMC has to be examined to ensure that CMC could be synthesized because of the proper attributes. AIM this research had been performed to determine the faculties of carboxymethyl cellulose synthesized using various solvents and NaOH concentrations. TECHNIQUES Carboxymethyl cellulose (CMC) was synthesized making use of solvent mixture, namely isopropanol isobutanol (30 70) and isopropanolethanol (50 50) with varied focus of NaOH of 5%, 10%, 15%, 20%, 25%, respectively. Synthesized CMC was described as an organoleptic test, pH, infrared analysis, and level of substitution (DS). RESULTS the effect revealed that characteristics of synthesized CMC were distinctive from each other. The organoleptic test indicated that synthesized CMC makes use of isopropanol isobutanol (30 70) was coarse powder, odourless and tasteless, ivory until burlywood along with increasing NaOH concentration; as the synthesized CMC with isopropanol ethanol (50 50) had been a colourless, odourless, tasteless and fine dust. The pH of synthesized CMC ended up being natural. Infrared profile of synthesized CMC indicated the presence of carboxyl practical teams in 1600-1640 cm-1 region. The amount of replacement value of formula II-5, II-10, II-15, II-20, II-25, IE-5, IE-10, IE-15, IE-20, and IE-25 had been 0.885;0.757; 0.685; 0.592; 0.575; 0.611; 0.906; 0.603; 0.671; 0.751, respectively. CONCLUSION traits of CMC vary depending on the sort of solvent combination and NaOH concentrations used in synthesis. The greater amount of polarity of a solvent mixture the more colourless and higher DS worth of synthesized CMC. On the other hand, the greater alkali concentration in synthesis CMC the more colour and greater DS price ended up being acquired. Copyright © 2019 Henny Sri Wahyuni, Sri Yuliasmi, Hanifah Siti Aisyah, Devi Riati.BACKGROUND North Sumatra is among the areas in Indonesia that produce bananas. Banana stems and skins contain cellulose and it can be isolated in nanofiber type. Carboxymethylcellulose is a cellulose derivative that goes through an alkalization and etherification process. AIM This research check details ended up being conducted to guage the alkalization influence on synthesis of carboxymethyl cellulose from stem and peel cellulose of banana. TECHNIQUES Stem and peel of banana had been extracted epigenetic stability with NaOH 17.5% while the extract ended up being synthesized to carboxymethyl cellulose (CMC). The forming of CMC was starting with alkalization procedure in difference of NaOH concentration additionally the reaction was then etherificated with salt monochloroacetate. CMC had been characterized by FTIR and DS values had been determined. OUTCOMES FTIR spectra of synthesized CMC had different structure in comparison to cellulose. It revealed that an etherification reaction was took place the cellulose element. Spectra of CMC with difference in alkali focus was not much not the same as the other person. The synthesized CMC from stem and peel cellulose of banana had various level of substitution (DS) values due to variate concentration of NaOH in alkalization. CONCLUSON Alkalization on CMC synthesis affects the DS value of synthesized CMC. The rise DS value is proportional towards the boost in NaOH concentration even though there clearly was a boundary focus to search for the optimum DS worth. Copyright © 2019 Sri Yuliasmi, Nahitma Ginting, Henny Sri Wahyuni, Ruth Theresia Sigalingging, Theophani Sibarani.BACKGROUND Turmeric extract is less effective since the primary ingredient of curcumin has actually a minimal solubility. Consequently, it is important to convert turmeric herb into a great dispersion type to increase the dissolution of curcumin. Try to figure out the anti-bacterial activity of mucoadhesive gastroretentive medication delivery system of alginate beads containing solid dispersion of turmeric plant.
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